CRi CRi

Skip to content

Digital Pathology Solutions

  • What makes these scanners so much better?

    They are among the fastest scanners available on the market today with the very best image quality. The Pannoramic MIDI and SCAN models are also multi-modal.

  • What is 'multi-modal'? Can the scanners automatically switch between brightfield and fluorescence?

    The Pannoramic SCAN and MIDI can be equipped for brightfield or both brightfield and fluorescence imaging. The low-cost Pannoramic DESK is designed for single-slide brightfield work only.

  • What software is included?

    Every scanner comes with Viewer, Database & Archiving software, as well as one image analysis software package of your choice:

    • HistoQuant: general-purpose, brightfield and fluorescence image analysis software
    • NuclearQuant: automatically scores your ER, PR and Ki-67 digital slides
    • MembraneQuant: automatic evaluation of HER-2 and EGFR samples
    • FISHQuant: automatic classification of FISH nuclei to normal, abnormal and artifact groups

    You can purchase additional modules beyond the first. inForm™, our very well-regarded advanced image analysis software program, is also available as an option. For teleconsultation , sharing and teaching purposes we also offer SlideServer and a convenient online resource Pathonet.org.

  • How can I share images of my slides with colleagues?

    You can, of course, save your images as TIFF or JPEG and send them as e-mail attachments. But we offer two more convenient, full-featured options: Slide Server and Pathonet.org. Slide Server allows you to consult with your colleagues either synchronized online or offline as requester/consultant with annotation available for each party's convenience. Pathonet.org is a free web portal that gives you access to your colleagues around the world. Registration and a nominal amount of online storage is free.

  • What is the difference between your whole slide imaging 'scanners' and your 'multispectral' imaging systems?

    Our scanners are designed for high-speed digitization of whole slides with high color fidelity and resolution. There is no better way to digitize your microscope slides for storage and sharing. Our multispectral imaging systems, Nuance and Vectra, are designed to enable multiplexing in intact tissue sections: detection and quantitation of multiple labels even if those labels overlap spatially or spectrally. Autofluorescence can be eliminated using CRi’s spectral unmixing technology.

  • If the new scanners let me use 9 channels for fluorescence, why do I need a Nuance or Vectra system for 'spectral unmixing' of my fluorescence images?

    If you are using FFPE sections, you will undoubtedly have an autofluorescence signal that reduces contrast and complicates your ability to detect and separate signals from multiple probes. Our Nuance and Vectra systems let you easily separate the overlapping autofluorescence signal from the signals that you want to see. For brightfield IHC slides, our multispectral imaging systems let you separate spatially and spectrally overlapping stains and better quantitate colocalization.

  • Can I use inForm on images taken with the scanners?

    You can save TIFF images using the scanners and inForm can open and analyze most types of TIFF images. Currently, inForm will open CRi multispectral (.im3) files as well as individual TIFFs.

  • Are there any service agreements or maintenance agreements available?

    Yes, we have a variety of options for services and maintenance of your scanner and software to suite your need. These are not yet posted on our website, but will be shortly.

  • What is the TMA Master?

    The TMA Master is a very compact, easy-to-use device for making your own tissue microarrays (TMAs). It lets you design and save your own templates and use different core sizes. It automatically drills your recipient blocks and punches your donor blocks with high precision. It does not come with a scanner, but could be purchased with one as a bundled package