Vectra™
High-content, high-throughput multi-label imaging without crosstalk
Vectra™ is the world's only multispectral fluorescence- and brightfield-capable microscope slide analysis system. Vectra's pattern recognition-based scanning rapidly acquires high-resolution multispectral images of samples on microscope slides. Samples can be cultured cells, cell spreads, tissue sections or tissue microarrays, stained with standard stains such as H&E or trichrome, or immunofluorescence and immunohistochemical techniques.
CRi's intelligent scanning approach, based on multispectral imaging, pattern recognition and machine learning, provides a more quantitative, more efficient and faster approach to harness reliable data from slides, compared to approaches that use color images acquired on whole-slide digital scanners. The Vectra system incorporates CRi's powerful image analysis software, called inForm™, and CRi's proprietary autofluorescence removal methodology. With this system, you can separate up to five fluorophores from one another and autofluorescence without cross-talk. The system is designed to perform batch processing of slides, up to 200 at a time, or for tissue microarrays.
Vectra automatically performs a low-power 4x scan of your tissue microarrays, extracting only relevant, interesting high-power 20x fields. Intelligent imaging provides a more efficient and faster alternative to whole-slide scanning. The period of time to perform a study can be reduced from months to weeks, even to hours.
| New Vectra single-slide | New Vectra 200-slide | |
|---|---|---|
| Automation | Single-slide | 200-slides without supervision |
| Stage Adjustment | Manual | Automated |
| Tissue Formats | Tissue microarrays (TMAs) and whole tissue sections | |
| Wavelength Range | 420 - 720 nm | |
| Throughput (based on intelligent field selection) | TMA: 3 cores/min Sections: 5-20 min per slide | |
| Modality | Brightfield of fluorescence (multispectral or color) | |
| Multiplexing capability | Separates markers, even overlapping, incl. autofluorescence | |
| Image Analysis (inForm™ software) | Intuitive learn-by-example interface, auto-segment and quantitate tissue structures, cells, sub-cellular signatures | |
| Magnification | 4x and 20x | |
| Barcode Reader | 1D/2D optional; reads MicroPDF, PDF 41, RSS, QR, Data Matrix, and other (1D) | |
| File Format | .im3 for multispectral (CRi); 24-bit TIFF for RGB | |
| Operating System | Windows™ XP Pro, SP-2 or later | |
| Computer | Quad Core Xeon, 1TB mirrored HDD minimum | |
| Required Bench Space | 6 x 2.5 ft | |
| Power Supply | 110/220 VAC | |
| CE Compliant |  |
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| Weight | 215 lbs, incl computer and two LCD monitors | |
