Assisted Reproductive Technologies
The visibility and location of the oocyte spindle have been shown to correlate with increased fertilization and embryo developmental potential, making the presence and orientation of a spindle a good marker for egg viability. Also important to egg viability is the molecular construct of the inner layer of the zona pellucida. CRi's Oosight Imaging System is uniquely capable of providing high-contrast quantitative images of the spindle and tri-laminar zona pellucida without the use of exogenous dyes or labels. CRi's Oosight system is currently used in hundreds of assisted reproductive technology (ART) labs worldwide to improve success rates of In Vitro Fertilization (IVF), somatic cell nuclear transfer (SCNT) and related applications.
Click on images to enlarge
Image 1: Human embryo with multipolar spindle. (D Hlinka Pronatal)
Image 2: Human MII oocyte in retardance pseudocolor. (RMA NJ)
Image 3: Human MII oocyte with SpindleFinder™ retardance overlay. (RMA NJ)
The Oosight system is meant for research purposes only.
